According to the recent observations the world climatic system undergoes essential changes. Some of them are associated with the El-Nino-Southern oscillation. This paper considers the circulation and its response to the sea surface temperature anomalies with the use of the ECSib global circulation model. The model simulation and circulation anomalies are compared based on the NCEP/ NCAR reanalysis supplementary datasets (the National Centers for Environmental Prediction-National Center for Atmospheric Research). It is found that the model reasonably simulates the spatial structure and variance of the sea level pressure and surface air temperature anomalies. The most distinctions between simulations and the observational data are in the middle latitudes over the midland areas of Eurasia, America and Africa. It is important that both the observations, and the numerical simulation clearly show the influence of the ENSO on the Asian monsoons, and hence, on those of the Central Asia.